Abstract: In view of problem of inconvenient routing in field of wire monitoring system of vibration signal of rolling bearing, a wireless collection system of vibration signal of rolling bearing was designed. The system uses acceleration sensor MMA7260 to collect acceleration signals of X, Y, Z axis of vibration signal of rolling bearing, and uses radio frequency transceiver chip nRF9E5 to transmit the signal to PC for analysis and processing, which realizes functions of collection and wireless transceiver with short distance for vibration signal of rolling bearing. The experiment result validated effectiveness of the system.